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Posts tagged “Science and Technology

Discovery of wound-healing genes in flies could mitigate human skin ailments | KurzweilAI

I never thought that I would find a reason to like flies, but this article has me thinking of them in a new way. God has a reason for everything and perhaps we are finally beginning to realize that even flies are important!

Discovery of wound-healing genes in flies could mitigate human skin ailments | KurzweilAI.

Biologists at UC San Diego have identified eight genes never before suspected to play a role in wound healing that are called into action near the areas where wounds occur.

Their discovery, detailed this week in the open-access journal PLOS ONE (open access), was made in the laboratory fruit fly Drosophila. But the biologists say many of the same genes that regulate biological processes in the hard exoskeleton, or cuticle, ofDrosophila also control processes in human skin.

“Many of the key molecules and proteins involved in Drosophila wound healing are involved in mammalian wound healing,” says Rachel Patterson, the first author who published the paper with Michelle Juarez and William McGinnis, a professor of biology and interim dean of the Division of Biological Sciences. “The genetics of Drosophila are not as complicated as mammalian genetics, so it’s easier to attribute specific biological functions to individual genes.” Read the rest at Discovery of wound-healing genes in flies could mitigate human skin ailments | KurzweilAI.

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Bringing people back from the dead | KurzweilAI

Bringing people back from the dead | KurzweilAI.

A doctor says people can be revived several hours after they have seemingly died, BBC News reports. Should this change the way we think about death?

“While 45 minutes is absolutely remarkable and a lot of people would have written her off, we now know there are people who have been brought back, three, four, five hours after they’ve died and have led remarkably good quality lives,” says Dr Sam Parnia, the director of resuscitation research at Stony Brook University in New York. Read more at Bringing people back from the dead | KurzweilAI.


3D printer makes tiniest human liver ever | KurzweilAI

3D printer makes tiniest human liver ever | KurzweilAI.

Lab-grown livers have come a step closer to reality thanks to a 3D printer loaded with cells, New Scientistreports.

Created by Organovo in San Diego, California, future versions of the system could produce chunks of liver for transplant.

The mini-livers that Organovo made are just half a millimeter deep and 4 millimeters across but can perform most functions of the real thing.Read more at 3D printer makes tiniest human liver ever | KurzweilAI.

Watch video at http://bcove.me/x9tub6fr


Nanosponges soak up toxins released by bacterial infections and venom | KurzweilAI

Nanosponges soak up toxins released by bacterial infections and venom | KurzweilAI.

Engineers at the University of California, San Diegohave invented a “nanosponge” capable of safely removing a broad class of dangerous toxins from the bloodstream — including toxins produced by MRSA, E. coli, poisonous snakes and bees.

These nanosponges, thus far studied in mice, can neutralize “pore-forming toxins,” which destroy cells by poking holes in their cell membranes. Unlike other anti-toxin platforms that need to be custom-synthesized for individual toxin type, the nanosponges can absorb different pore-forming toxins regardless of their molecular structures. Read more: Nanosponges soak up toxins released by bacterial infections and venom | KurzweilAI.

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New injectable hydrogel encourages regeneration and improves functionality after a heart attack | KurzweilAI

 

New injectable hydrogel encourages regeneration and improves functionality after a heart attack | KurzweilAI.

University of California, San Diego bioengineers havedemonstrated in a study in pigs that a new injectable hydrogel can repair damage from heart attacks, help the heart grow new tissue and blood vessels, and get the heart moving closer to how a healthy heart should.

The gel is injected through a catheter without requiring surgery or general anesthesia — a less invasive procedure for patients.

There are an estimated 785,000 new heart attack cases in the United States each year, with no established treatment for repairing the resulting damage to cardiac tissue.

Lead researcher Karen Christman, a professor in the Department of Bioengineering at the UC San Diego Jacobs School of Engineering, said the gel forms a scaffold in damaged areas of the heart, encouraging new cell growth and repair. Because the gel is made from heart tissue taken from pigs, the damaged heart responds positively, creating a harmonious environment for rebuilding, rather than setting off a chain of adverse immune system defenses.

“While more people today are initially surviving heart attacks, many will eventually go into heart failure,” said Christman.  “Our data show that this hydrogel can increase cardiac muscle and reduce scar tissue in the region damaged by the heart attack, which prevents heart failure. These results suggest this may be a novel minimally invasive therapy to prevent heart failure after a heart attack in humans.” Read the rest at New injectable hydrogel encourages regeneration and improves functionality after a heart attack | KurzweilAI.

 


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